The first mention of the Church of San Frediano relate to 1061. It was founded by the family of Boccaccini-Sismondi and was originally dedicated to St. Martin. Once near the Church is a hospital.

The Romanesque facade of San Frediano, the typical medieval architecture of Pisa. It is decorated with blind arches, diamond shapes and dichroic stones, which were also used in the construction of the city's Cathedral. In the upper part of the facade you can see a huge arched window. The interior, despite the terrible fire of 1675, in a fairly good condition. The Church has a typical Basilica plan of a Central nave and two lateral chapels. Marble capitals of the columns are decorated with stucco figures in Romanesque style. Among stored here works of art can highlight a rare Grand cross of the 12th century, painted on gilded panels, several Baroque altars restored in the 16th and 17th centuries, and paintings from the 17th century brush Ventura of Palio depicting "the Annunciation" and "Christmas". Aurelio Lomi owns the painting "adoration of the Magi". And numerous frescoes – is the work of Domenico Passignano. The dome was painted by the artist Rutilio the Manetti. Above the apse is a window in the center of which you can see the coat of arms of the Agostini family, patrons of the Church.

Near the Church of San Frediano stands sturdy brick bell tower. Interestingly, there is a number of offices of various social movements and associations, for example, Leaning branch of the Italian Catholic Federation of Students, Association of Catholic students, the Association "Santa Malatesta", which provides assistance to foreign students coming to Pisa from countries experiencing war or from countries with a high poverty level.