On the left Bank of the river to the long sandy beaches at the foot of St. Sergius mountains in the late sixteenth century the Moscow Streltsy, particularly stepsine of St. Sergius of Radonezh, the temple was built. In place of the existing in our days of the building of the Cathedral, which once stood two wooden Church that burned consistently in 1774 and 1860.

In 1868 was consecrated a new wooden building of St. Sergius Church, built on a stone base. Modest architectural plan of the temple, reminiscent of a rural parish Church, was loved and respected by the townspeople. In 1933, after the destruction and closure of all churches and cathedrals, the little Church became the Cathedral of the Ufa diocese. From 1937 to 1942, the clergy of St. Sergius Cathedral were arrested and shot (for which the service is practically not carried out), but the temple "graciously" remained open to parishioners. All the Soviet years St. Sergius Cathedral was the center of Orthodox life in the Ufa region. In 1942, the Church returned the priests – the former inmates of the camps, and in 1945 the Church received a commendation for raising funds for the defense of the country.

In our days the oldest building of the temple, and again subjected to major repairs with replacement of the wooden elements of construction for a more durable material, decorates the historical center of Ufa. In the Church there is an icon with the relics of St. Sergius of Radonezh, St. Nicholas and other saints. On the territory of the temple is the source of Holy water and baptismal font, as well as the tombs of the governors of the former monastery, also known as the cave). 2000. on the day of the Holy Trinity from the temple every year begins a five-day religious procession (dedicated to the founding of the city in 1574) around Ufa, with visits to suburban churches.