The Church Of St. Sebastian is a small Church in the city of Dubrovnik. According to historians, it was built in medieval times to serve the residents protection from the plague. The temple is located in the old part of the town near the Dominican monastery, the entrance gate of Ploce.

The Church Of St. Sebastian is the first architectural structure of Dubrovnik, in the style of the Renaissance. The semicircular apse of the Church is characteristic of Renaissance architecture.

The construction of the Church took place under the guidance of masters of Vlatko Descovich and Mihoci Radisich and was completed in 1466. In the next few years on other parts of the temple and architectural ornaments worked by local craftsmen. The Church is crowned by a graceful triple bell tower, typical of many churches in Dalmatia.

In the 15th century the Church was the Guild of gunners, and in 1808, during the French occupation, the Church. Sebastian was a prison. Today in the Church is the gallery of "Sebastian", which organizes various cultural events and exhibitions.

Under the Church are warehouses owned by situated ibid stonecutting workshops.