The small Church of Santa Ana is located in the centre of Granada, Plaza Nueva, next to the Royal Chancellery at the foot of the Alhambra. This Church was built in 1537 under the project of the famous architect and painter of the time of Siloam Diego. Like many other churches built in that period, the Church of Santa Ana was built on the site of a former mosque al-Yama Almanzora. The minaret of the mosque that represents beautiful and thin brick tower, traditionally was saved and rebuilt in the belfry.

The exquisite facade of the Church with five chapels, ceilings decorated in the Mudejar style, adorned with magnificent portal in the plateresque style. The interior of the Church of Santa Ana is made in Baroque style. The chapel is decorated with sculptural elements on its walls there are paintings Dating back to the 16-17 centuries. In the Church sacristy is kept amazing bowl created by Francisco Telesom in 1568. The main entrance to the Church began to create the architect sebastián de Alcantara in 1542, and completed by his son Juan de alcántara in 1547. The entrance is made in the form of an arch that lies between the Corinthian columns. The entrance is decorated with three beautiful sculptures made by master Diego Aranda and arranged in three compartments. Above them is a beautiful round locket or Tondo with a relief depicting the virgin Mary with the infant.

The Church of Santa Ana is a structure in which a surprising combination of styles, typical of Moorish architecture and Renaissance architecture.