The Saviour Orthodox monastery in Kobrin was probably founded in the XVI century. Although the exact date of its Foundation is not preserved, it is known that the monastery was established on the initiative last Kobrin Prince Ivan Semenovich. Subsequently, his widow, son and daughter-in-law made many contributions to the Spassky monastery.

In 1465 Princess Ulyana Kobrin as a gift to the monastery was transferred to a mill and extensive grounds, and other property. Spassky monastery was a rich and prosperous. In 1492 Princess Fedor Ivanovna gave some of their land and immovable property in favour of the monastery. When in the early sixteenth century, the Princess turned to Catholicism, she tried to take away a part of the donated land from the monastery, however, after the claim of Archimandrite Kobrin of Vasian, land was returned to the monks.

After the signing of the Union of Brest in 1596, the monastery was almost full squad, keeping all their belongings, passed into the Union. Last Archimandrite Jonah became Turov-Pinsk Bishop.

In the XVII century the monastery was like a state within a state. He owned many villages and farms.

The monastery was badly damaged during the war of 1812. Buildings suffered significant damage, and while Kobrin battle June 27, 1812 burned down the ancient wooden monastery Church.

In 1839 the Union was abolished, and the monastery was closed. Within its walls was organized by the religious school, and the main building stood in ruins. In the 1920s, the Polish authorities did in the main building major renovation, during which it was completely rebuilt in civil construction, the remains of the monastic decor were destroyed. In the years of the Polish-Lithuanian Commonwealth was occupied by a court. In the years of Soviet power in the walls of the former head of the monastic body was found the police station.

June 29, 2010, the building was returned to the Orthodox Church. November 20, 2010 there was organized a women's monastery. In 2011, the monastery was delivered a list with revered icons of the Mother of God "quick to hearken". The revival of Orthodox monastery, after four centuries Christians believe miracle.