The history of the hospital De Los Venerables, located in the capital of Andalusia – Seville, started in the 17th century. It was then that the religious Brotherhood of Silence was founded a home for the sick and elderly of the Church, rebuilt later in the hospital. The hospital occupied the building, located today in the Santa Cruz, the Plaza De Los Venerables, and built in the 17th century in Baroque style by the architects Juan Dominguez and the famous Leonardo de Figueroa.

In 1689 to the building was completed the Church, dedicated to St. Fernando. The Church has one nave, the Central altar is decorated with paintings of artists of Valdez Leal and his son Lucas Valdes. The ceiling and walls of the Church also painted by Lucas Valdes. Near the altar are relief figures of San Juan Bautista and San Juan Evangelista, performed martínez Montanyes.

Another feature of the hospital building is its beautiful, typical Andalusian patio, planted with green trees and surrounded by two-storied gallery.

In 1805, the hospital fell into decay, the brotherhood was virtually no funds to support it. In 1840 an attempt was made to take away belonging to the brotherhood of the building to accommodate textile factory here, but after numerous complaints in 1848 by order of the king, the hospital was returned to its owners.

Since 1991 in the building of the hospital De Los Venerables is the Cultural Foundation of Seville, in the period from 1987 to 1991 held the repair and restoration of the premises of the hospital. Today, frequently, exhibitions, concerts, conferences and seminars devoted to art.