Chapel of Saint Roch in the Croatian city of Vukovar is located on Zupanijskoj the street, which is the main street of the city. The chapel was built on donations of Antoine of Pokhra de Rosenthal in gratitude for deliverance from the plague and as a support Church for German settlers in this part of town. It was consecrated in honor of St. Roch, St. Sebastian and St. Rosalia. Catholics believe that St. Roch protector from the plague.

According to the legend of St. Roch was the son of the Governor of Montpellier, marked at birth on breast sign having the shape of the red cross. After his parents died, he at the age of 20 went on pilgrimage to Rome, pre-distributing the property to the needy. In Italy at this time was raging plague. St. Rox traveled around the country and healed the sick through prayer and the sign of the cross. Francis himself contracted the plague and was saved from starvation by a dog who brought banished from the city of St. Roch in forest hut bread. Soon St. healed.

The original chapel building was built in the Baroque style. In 1805 were added lateral oratorio and sacristy, and the picturesque bell tower was covered with tiles. Subsequent reconstructions were made in 1858 and 1904, and after the Second world war. After the war the sponsor of the reconstruction made Šibensko-Kninska County. Since 1998, the updating of the chapel of St. Roch, expiration date of recovery was postponed several times.